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Best NFL Prediction Market Apps for Week 1 This Weekend: Sunday Slate and Monday Night Football

September 9, 2026
by Emma Harrison

The NFL 2026 season is in full swing and Week 1 kicks off with 16 games being played on Wednesday, Thursday, and Sunday. This includes the Seahawks and Patriots, and Bills and Texans which should be epic showdowns.

Alongside the games from NFL Week 1, one of the best pieces of prediction market news is that top prediction market apps like Kalshi and Polymarket have a host of predictions you can trade on, including overall winners and spreads. Read on to see the 4 standout matches SailGP has picked, highly anticipated games packed with action and plenty of trade contract opportunities at these exchanges..

Top predictions for NFL Week 1 games

Although there’s 16 games this week, we thought the following four were the best options for NFL prediction markets:

Seattle Seahawks vs. New England Patriots

Prediction ExchangeSeattle to winImplied ProbabilityNew England to winImplied probability
Kalshi63c62%38c38%
Polymarket63c62%38c38%

LA Rams vs. San Fancisco 49ers

Prediction ExchangeLA to winImplied Probability49ers to winImplied probability
Kalshi64c65%36c36%
Polymarket65c65%36c36%

Houston Texans vs. Buffalo Bills

Prediction ExchangeHouston to winImplied ProbabilityBuffalo to winImplied probability
Kalshi51c51%50c50%
Polymarket51c51%50c50%

Philadelphia Eagles vs. Washington Commanders

Prediction ExchangeEagles to winImplied ProbabilityCommanders to winImplied probability
Kalshi69c69%33c33%
Polymarket69c69%32c32%

Reviewing the best prediction market apps that have these NFL markets

To finish, let’s take a look at the sites that are offering the best prediction markets and what else they offer:

Kalshi – great for live NFL predictions

Kalshi: Pros & Cons
  • Broad range of markets
  • 24/7 live chat support
  • Huge reputation
  • Native mobile app
  • Transaction fees

As mentioned in our Kalshi review, this operator has the highest trade volume, plus low trading fees. This means you get the flexibility to make the NFL trades you want. Not only that, but it has a live sports prediction section, so you can trade as you watch the above games. Aside from football, the Kalshi sports predictions also include basketball, soccer, tennis, golf, and a handful of other popular sports. It’s not just sports though, and it has one of the largest event prediction collections available. You’ve got everything from crypto prices and election predictions to culture, climate, and economics.

Polymarket – high-quality mobile apps

Polymarket: Pros and Cons
  • Numerous markets on sports, crypto, the economy, and politics
  • Regulated by the CFTC
  • Multiple rewards for existing traders
  • Crypto payments only

Polymarket also features live NFL predictions, and while it has overall winner markets, it has futures predictions too, plus other in-game stats like 1st and 2nd half splits, exact margins, and team totals. For most of the matches, it has impressive trade volume too, which means that you should be able to easily get your orders matched. As you’ll see from our Polymarket review, one of the standout features of this exchange is its usability. The desktop website looks clean and modern, but there’s also two downloadable apps offering a superior NFL mobile trading experience.

Crypto.com – versatile banking setup

Crypto.com: Pros and Cons
  • Welcome bonus
  • Broad range of markets
  • High-performance mobile app
  • Strict ID verification

Lastly we have Crypto.com which offers <$, $1, and $10 trade contract base values, you don’t need a promo code to get this offer.. This is great for flexibility and means you can trade as much or as little as you want. It doesn’t have NFL prediction markets, but you can trade NCAA college football predictions instead. It has the largest selection of college football predictions and covers games in all States. Instead of a variable trading fee, Crypto.com makes things easier with flat trading and exchange fees so you can easily work out what you are actually paying. This is usually capped at $0.01 per transaction per contract, so a total max fee of $0.02.

Get in on this week’s NFL action and trade some predictions

If you want one must-see match this week, we recommend the Seahawks vs. Patriots. Who wouldn’t want to see the reigning Super Bowl champs start their campaign to defend their title? While you’re watching, don’t forget that you can also trade predictions for these games at Kalshi, Polymarket, and Crypto.com – you can sign up at any of them by clicking the banners we’ve got on this page.